The cost of implementing the C-MAMI tool to treat nutritionally vulnerable infants in Bangladesh
By Natasha Lelijveld, Mostofa Sarwar, Golam Mothabbir, Sarah Butler and Nicki Connell
Natasha Lelijveld is a Research Fellow at the Centre for Global Child Health at the Hospital for Sick Kids in Toronto. She has previously worked on acute and chronic malnutrition research at University College London, London School of Hygiene and Tropical Medicine and the No Wasted Lives initiative at Action Against Hunger.
Mostofa Sarwar is a medical doctor with five years’ experience in maternal and child health and nutrition in development and emergency contexts with leading non-governmental organisations (NGOs). He is currently the Deputy Manager- Health, Nutrition and HIV/AIDS for Save the Children in Bangladesh.
Golam Mothabbir is the Senior Advisor for Health and Nutrition at Save the Children International, Bangladesh Country Office. He has been providing technical and strategic guidance to the MAMI field research team in Bangladesh since August 2014.
Sarah Butler is the Director of Emergency Nutrition at Save the Children, US. She has more than ten years’ experience in nutrition and has been leading the team since Save the Children began implementation research into C-MAMI in 2013.
Nicki Connell is currently the Eleanor Crook Foundation’s Nutrition Technical Director. Nicki was previously an Emergency Nutrition Advisor for Save the Children, and served as Project Manager for this work. She has ten years’ experience in emergency nutrition, with much experience in the management of at-risk mothers and infants (MAMI).
The authors would like to thank Dr Marko Kerac from London School of Hygiene and Tropical Medicine for his academic support, Save the Children for hosting the fieldwork within their programmes, and the in-kind expertise provided by the No Wasted Lives initiative at Action Against Hunger UK.
What we know: The C-MAMI tool was developed to guide the community-based management of uncomplicated cases of severe acute malnutrition (SAM) in infants under six months, as per the WHO 2013 guideline.
What this article adds: Save the Children carried out a calculation of the cost-efficiency of a protocol based on the C-MAMI tool in Bangladesh, compared to the standard, inpatient-based protocol. Costs were identified for both protocols, including inputs, health system costs, efficiency data (such as number of admissions/month), scale-up costs and costs to caregivers. The cost of C-MAMI to the healthcare provider (per clinic/month) was higher than the standard (USD1,007 vs USD466); however, it was found to be more cost efficient per infant treated (USD289 vs USD685). If fully integrated into the national health system, the cost of C-MAMI would reduce to an estimated USD536 per clinic/month and USD154 per infant treated. The cost for caregivers was found to be lower for C-MAMI compared to the standard (USD53 vs USD74 per caregiver/six months). Overall, the societal costs (healthcare provider + caregiver) were significantly lower in C-MAMI compared to standard (USD342 vs USD759), although both were judged to be cost-efficient.
Current treatment guidelines for severe acute malnutrition (SAM) in infants under six months are based on very weak evidence and focused on inpatient care; WHO guidance recommends community-based management for uncomplicated cases (WHO, 2013). To help a fill a gap in programming guidance, the C-MAMI tool was developed to help catalyse community-based case management. Save the Children (SC) recently tested a protocol based on the C-MAMI tool for the treatment of “nutritional at-risk” infants in Barisal district, Bangladesh, estimating its effectiveness compared to the current standard inpatient protocol (results pending).
A secondary aim of the research was to calculate the cost and cost-efficiency of this new treatment method. This economic sub-study aimed to highlight major considerations in cost differences between standard inpatient protocol and the C-MAMI model from a societal prospective, considering costs to both the healthcare provider and caregivers.
The C-MAMI model (intervention) and standard inpatient protocol (control) were implemented in 24 community clinics in Barisal district within the Ministry of Health (MoH) system, with support from SC staff. All infants receiving C-MAMI support were requested to attend weekly counselling appointments at the clinic and received home visits as necessary.
To estimate costs, programme inputs (“ingredients”) were identified and quantified and costs were assigned against these, informed by the study protocol, accounting data and expert observation. A simple decision tree was built to map the various treatment pathways in each study arm and guide the mapping of major resources for inclusion in cost calculations (Figure 1). Due to the integrated nature of the programmes, other health system costs were estimated through key informant interviews and published WHO-CHOICE values1. Efficiency data, such as the number of admissions per month, were calculated from interim values at the time of costing data collection.
Using information from the FANTA II Profiles results for Bangladesh, we also present the estimated cost for scaling up the implementation of the tool within an integrated health system, and this cost in relation to published government spending (Howlader, 2012).
Costs to caregivers, including direct costs and indirect time costs, were estimated through informal, anonymous interviews with a range of caregivers; programme defaulters are likely underrepresented.
Figure 1: Decision trees for the control treatment model and the intervention treatment model
There are several key differences between the C-MAMI model and the standard protocol which need to be considered from a cost perspective. The C-MAMI model has a wider range of admission criteria, including maternal health indicators, and the treatment consists largely of weekly counselling and specialised lactation advice, compared to inpatient-feeding based on infant anthropometry only in the standard protocol.
Cost to healthcare providers
For the healthcare provider, the cost of the C-MAMI intervention was higher than the standard intervention (USD1007 vs USD466 per clinic per month), due to additional staff, staff training, tablet computers (for the MAMI app which accompanied the protocol), and capital costs of creating breastfeeding corners (Table 1). However, when this cost is applied to the number of children treated by each clinic each month (3.5 vs 0.7), the C-MAMI intervention becomes more cost-efficient than the standard model (USD289 vs USD685 per child treated).
Table 1: Summary of cost to the health provider for the intervention and the control models
Estimated cost if the C-MAMI intervention was fully integrated with national MoH
The above costs are based on the current system, which is supported by SC staff. If the C-MAMI protocol were to be fully integrated into the national health system, it would streamline and save costs. These hypothetical cost calculations include more Community Health Volunteers (CHVs) in place of Field Officers for screening, training Health Assistants to make referrals and home visits, and utilising Family Welfare Assistants to replace the role of SC Technical Officers as lactation specialists. The tablet computers would still be necessary to use the C-MAMI app. High-level staff training is still required; although associated cost and time is high, it is fundamental to the successful treatment of infants <6m and could be more cost-effectively implemented if conducted on a larger scale. Table 2 presents the summary of costs for this hypothetical “streamlined” and “fully integrated” intervention model.
If considering the scale-up to national level, based on an estimate of 17,700 community clinics in Bangladesh, the cost of implementing C-MAMI for one year at a national level would be USD114 million.
Table 2: Estimated cost of a fully integrated MoH C-MAMI intervention model
Cost to caregivers
Despite the additional time and money spent on weekly clinic visits, the overall cost is lower for caregivers in the C-MAMI intervention than the standard protocol (average USD53 vs USD74 per caregiver for six months). The C-MAMI programme saved some caregivers the high cost of lengthy inpatient admissions and the need to seek additional private health advice. Successful relactation through the C-MAMI lactation support also saved the cost of breastmilk substitute (BMS) where applicable.
Table 3: Cost to caregivers of the intervention vs control treatment protocols
Costs from a societal perspective
The societal cost per child treated (health provider + caregiver) by either the C-MAMI intervention (USD342) or the standard protocol (USD759) was less than the Bangladesh 2016 per capita GDP (USD1,358.8), which suggests that both models are “cost-effective”. Based on estimates from a FANTA report, the cost of implementing the “integrated” C-MAMI protocol for one year at a national level (USD114million) is approximately 11% of the Bangladesh 2012 Health Promotion and Nutrition budget, which seems attainable.
This study could not calculate any additional cost-savings of the intervention in potentially preventing infant SAM cases, preventing child stunting, and reducing the burden of severe wasting in children aged 6-59 months; however, these factors should be considered by policy-makers. In addition, it will be important to calculate the “cost per recovered” once the main study results have been analysed.
The absolute cost per clinic of the C-MAMI intervention is higher from a healthcare provider perspective than the cost of the standard control protocol, but is more cost-efficient per child treated and less costly to caregivers. A national, integrated C-MAMI intervention is potentially viable at scale. It is important to reassess cost-effectiveness of treatment approaches in light of potential SAM cases averted, if data is available. Additional cost-savings in preventing malnutrition and in reducing severe wasting burden in children aged 6-59 months should also be considered when evaluating the cost-effectiveness of the C-MAMI intervention.
1The WHO-CHOICE project (CHOosing Interventions that are Cost-Effective) has a database of region-specific costs for common health interventions to help policy-makers assess cost-effectiveness of health programmes, including for Bangladesh specifically.
Islam, M., et al., Severe malnutrition in infants aged <6months- seasonal prevalence, outcomes and risk factors in Bangladesh: repeat cross sectional surveys and a prospective cohort study. Under Consideration, 2018.
Islam, M.M., et al., Risk factors for severe acute malnutrition in infants <6 months old in semi-urban Bangladesh: A prospective cohort study to inform future assessment/treatment tools, in ACF Research Conference. 2016, ENN Field Exchange. p. 62.
Read, S., Improving community management of uncomplicated acute malnutrition in infants under six months (C-MAMI): Developing a checklist version of the C-MAMI tool. Field Exchange, 2017. 54(February 2017): p. 30.
Howlader, S.R., et al., Investing in nutrition now: a smart start for our children, our future. Estimates of benefits and costs of a comprehensive program for nutrition in Bangladesh, 2011–2021. PROFILES and Nutrition Costing Technical Report. Washington DC, USA:
Food and Nutrition Technical Assistance III Project (FANTA), 2012. Food and Nutrition Technical Assistance III Project (FANTA), FHI, 2012. 360.
WHO (2013) Updates on the management of severe acute malnutrition in infants and children. Available here.
More like this
View this article as a pdf This issue of Field Exchange features six articles on managing nutritionally vulnerable infants under six months of age. This MAMI 1 section...
By Anne Marie Kueter, Claudine Prudhon, Emily Keane and Megan Gayford The implementation of community-based management of acute malnutrition (CMAM) as the standard model of...
By Anne Marie Kueter, Alice Burrell, Sarah Butler, Mostofa Sarwar and Habibur Rahaman View this article as a pdf Anne Marie is a nutritionist with over five years'...
By Sarah Butler, Nicki Connell and Hatty Barthorp View this article as a pdf Sarah Butler is the Director of Emergency Nutrition at Save the Children, USA. She has more than...
FEX: The Paediatric Development Clinic: A model to improve medical, nutritional and developmental outcomes for high-risk children aged under-five in rural Rwanda
By Kathryn Beck, Catherine M Kirk, Jessica Bradford, Christine Mutaganzwa, Evrard Nahimana and Olivier Bigirumwami View this article as a pdf Kathryn Beck is the Nutrition...
A one-day meeting of the Management of At risk Mothers and Infants (MAMI)1 Special Interest Group (SIG) took place in London on 17 January 2018. The meeting was hosted by ENN...
Dr Ferew, MOH Advisor, Government of Ethiopia, addressing the consultation on Day 1 The Alive and Thrive Project1 is supporting a two-year, field-based study on the...
FEX: Management of severe acute malnutrition by community health workers: Early results of Action Against Hunger research
View this article as a pdf By Pilar Charle-Cuellar, Noemi Lopez-Ejeda, Magloire Bunkembo, Abdias Ogobara Dougnon and Hassane Toukou Souleymane Pilar Charle Cuellar is a...
FEX: Community management of uncomplicated malnourished infants under six months old: barriers to national policy change
By Sonja Read and Marie McGrath View this article as a pdf Sonja Read is a public health nutritionist and was lead researcher (ENN consultant) on the project. Marie McGrath...
Donors: Irish Aid Collaborators: LSHTM, University of Washington, KEMRI-Wellcome Trust Project and CHAIN (Kenya), WHO, UNHCR, UNICEF, Save the Children, ACF, Goal, MSF, World...
FEX: Improving community management of uncomplicated acute malnutrition in infants under six months (C-MAMI): Developing a checklist version of the C-MAMI tool
Summary of MSc project report1 By Sonja Read Sonja Read is a public health nutritionist from the London School of Hygiene and Tropical Medicine. She has previously worked in...
FEX: Management of acute malnutrition in infants less than six months in a South Sudanese refugee population in Ethiopia
By Mary T Murphy, Kassahun Abebe, Sinead O'Mahony, Hatty Barthorp & Chris Andert View this article as a pdf Lisez cet article en français ici Sinead O'Mahony is a...
Summary of study1 Bangladesh has the fourth-highest number of children (approximately 600,000 at any one time) suffering from severe acute malnutrition (SAM) in the world....
Summary of report1 Child malnutrition is a major global public health issue. The burden of acute malnutrition in children 6 months to 5 years is well recognised, and the...
Summary of research1 Location: Bangladesh What we know: The World Health Organization (WHO) recommends that infants under six months with uncomplicated severe acute...
On 27th January 2016, ENN, London School of Hygiene and Tropical Medicine (LSHTM) and Save the Children co-hosted a one day meeting of a Management of Acute Malnutrition in...
NEX: Perceptions of severe acute malnutrition and its management in infants under six months of age: An exploratory study in Bangladesh
Yasir Arafat1is a medical doctor and public health practitioner, managing community-based nutrition programmes targeting acute malnutrition. He is currently working with Save...
Summary of Research Isanaka S, Menzies NA, Sayyad J, Ayoola M, Grais RF and Doyon S. (2016). Cost analysis of the treatment of severe acute malnutrition in West Africa. Matern...
FEX: Cost effectiveness of community-based and inpatient therapeutic feeding programmes to treat SAM in Ethiopia
Health Extension Worker testing the appetite of a malnourished child, Menkere health post, Tigray region By Asayehegn Tekeste, Kebede Deribe, Dr Mekitie Wondafrash and Dr...
View this article as a pdf By Bethany Marron, Pamela Onyo, Eunice N Musyoki, Susan Were Adongo and Jeanette Bailey Bethany Marron is a nutrition advisor and former ComPAS...
Reference this page
Natasha Lelijveld, Mostofa Sarwar, Golam Mothabbir, Sarah Butler and Nicki Connell (2018). The cost of implementing the C-MAMI tool to treat nutritionally vulnerable infants in Bangladesh. Field Exchange 58, September 2018. p55. www.ennonline.net/fex/58/cmamitoolbangladesh